Macron made this known at the opening of a summit in Mali’s capital, Bamako this Sunday.
Leaders of the G5 Sahel bloc – Mali, Burkina Faso, Mauritania, Niger and Chad are expected to launch a new multi-national force at the meeting.
The force which Macron hopes will be operational in the coming weeks is aimed at combating Islamist militants and illegal activity in the vast arid zone.
“Every day we must combat terrorists, thugs, murderers … who we must steadfastly and with determination eradicate together,” said Macron, who was making his second visit to Mali since taking office in May.
Islamist militant groups, some with links to al-Qaeda, seized control of Mali’s desert north in 2012.
While they were driven out of major cities and towns a year later by a French-led military intervention, they continue to carry out attacks against UN peacekeepers, Malian soldiers and civilian targets.
The violence has spilled over into neighbouring countries in West Africa’s Sahel region and Paris has deployed thousands of French troops to combat Islamists as part of a cross-border operation known as Barkhane.